Faculty
David Shang, D.D.S., Ph.D
Education:
D.D.S., Western China University of Medical Sciences, Sichuan, China
Ph.D. in Mol. Biology, Western China University of Medical Sciences, Sichuan,China
Current Position: Postdoc Fellow (since July, 2004)
Project: Biosynthesis and Intracellular Sorting of ADAMTS13 in Endothelial and Epithelial Cells
Hobbies: Plays tennis
Publications:
- Shang D., J. Ai, Li N and X. Zheng
Apical sorting of ADAMTS13 in endothelial and MDCK cells depend on CUB domains and its interaction with detergent-insoluble glycosphingolipid- and cholesterol-enriched rafts
J. Biol. Chem. 2006 In press. (2005
Masami Niiya, M.D., Ph.D.
Education:
M.D., Ph.D. in Internal Medicine, Okayama University, Okayama, Japan
Current Position: Postdoc Fellow
Project: Biological Functions of ADAMTS13 metalloprotease in vivo
Hobbies: Plays baseball and tennis
Publications:
- Niiya M, Uemura M, Zheng XW, Dockal M, Scheiflinger F, Wells R, Pollak E and X. Zheng
Enhanced ADAMTS13 proteolysis in hepatic stellate cells upon activation and in liver after carbon tetrachloride administration
J. Thromb. Hemost. 2006, In press. (2005
Shenyu Jin (Kim), MD, PhD
Education:
M.D.Yanbian University College of Medicine, Jilin, China
Ph.D. Molecular Biology,Kyung Hee University, Seoul, South Korea
Current Position: Postdoc Fellow
Project: Structure determination of ADAMTS13 domains by NMR and crystallography
Hobbies: Plays soccer
Publications:
- In Progress
Sara C. Meyer, M.D.
Education:
Medical school University of Bern, Switzerland, M.D. (Medicine).
Current Position: Postdoc fellow and exchange scientist (since 2007)
Project: Molecular characterization of ADAMTS13 mutations found in hereditary and acquired thrombotic thrombocytopenic purpura.
Hobbies: Hiking & Jogging, playing violin.
Publications:
- Meyer SC, Sulzer I, Laemmle B., Kremer Hovinga JA.
Hyperbilirubinemia interferes with ADAMTS13 activity measurement by FRETS-VWF73 assay – Diagnostic relevance in patients suffering from acute thrombotic microangiopathies.
Date: 2007
J Thromb Haemost 5(4):866-7. - Meyer SC, Largiader CR., Jin S., X.L. Zheng, CA. Dahinden, JN George, B Lammle, and JAK Hovinga.
The ADAMTS13 Gene as the immunological culprit in acute acquired TTP- first evidence of genetic out-breeding depression in humans.
Date: 2007
Abstract submitted to The 49th ASH Annual Meeting, Atlanta, George.
Wenjing (Wendy) Cao, M.D., Ph.D.
Education:
Tongji Medical College, Huazhong University of Science and Technology, China, M.D. (Medicine)
Tongji Medical College, Huazhong University of Science and Technology, China, Ph.D. (Hematology)
Current Position: Postdoctoral Fellow (since September 2006)
Research Project: Cofactors-dependent regulation of ADAMTS13 function
Hobbies: Jogging and playing table tennis
Publications:
- Cao WJ, Krishnaswamy S, PS Lenting and XL Zheng.
Factor VIII, a cofactor for accelerating proteolytic cleavage of von Willebrand factor by ADAMTS13.
Date: 2007
Abstract submitted The 49th ASH Annual Meeting, Atlanta, George.
Fernanda Orsi, M.D.
Education:
School of Medicine of the State University of Campinas (UNICAMP), Brazil, M.D. (Medicine).
School of Medicine of the State University of Campinas (UNICAMP), Brazil, Residency (Hematology and Hemotherapy).
Current Position: Visiting Physician Scientist (since September 2007)
Research Projects:
Characterization of ADAMTS13 deficiency and autoantibodies in patients with thrombotic thrombocytopenic purpura.
Determination of ADAMTS13 activity, VWF antigen and activity as well as multimers in patients with hemophilias.
Hobbies: Running and diving.
Publications:
- In progress
X. Long Zheng, M.D., Ph.D.
Assistant Professor, Pathology and Laboratory Medicine
Education:
College of Medicine, Nanchang University M.D. (Medicine)
University of Vienna, Austria Ph.D. (Mol. & Cell Biology)
Washington University, St. Louis, MO Residency and fellowship (Clinical Pathology
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